在进行产前诊断时,为估计羊水细胞培养中超众数细胞的频率和临床意义,鉴别真嵌合型和假嵌合型,作者对2,029例羊水标本进行了观察。超众数细胞是指那些多于46个染色体,有一个附加的正常结构或异常结构染色体为特点的细胞。对那些辨认不清的无着丝粒断片或染色体断裂分成两部分计数,存在47条以上的“染色体”时,可认为是假超众数细胞,不包括在超众数细胞内。2,029例标本中,主要是高龄产妇(占 In the prenatal diagnosis, in order to estimate the frequency and clinical significance of the supercells in amniotic fluid cell culture, authentic chimeric and pseudomimetic types were identified. The authors examined 2,029 amniotic fluid samples. Supercells cells are those cells that are characterized by more than 46 chromosomes, with an additional normal or abnormal structural chromosome. For those unidentified fragments or chromosome breakage is divided into two parts count, there are more than 47 “chromosome”, can be regarded as false super-minority cells, not included in the super-minority cells. Of the 2,029 specimens, mainly older mothers (accounting for