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目的 分析三亚市消灭脊髓灰质炎(以下简称脊灰)不同阶段的免疫策略与效果,为消灭及控制其它疫苗相关疾病提供经验。方法 收集不同阶段所采取的免疫策略,分析实施后产生的效果。结果 不同免疫阶段所产生的效果不同,消灭脊灰阶段免疫策略产生的效果最显著。脊灰疫苗常规免疫接种率持续保持在85%以上,22轮次强化免疫接种率均达95%以上,人群抗体在1:400高免疫策略阶段脊灰年发率呈连续下降趋势,监测系统监测资料证实三亚市1993年4月后已连续8年无脊灰野病毒感染病例发生。实现全市无脊灰状态。消灭脊灰以来减少家庭经济负担1,533万~8,390万元,创造效益1,234万~6,669万元。结论 三亚市通过实施消灭脊灰免疫策略,已达到阻断脊灰野病毒的循环,在产生了显著的经济效益同时也产生了巨大的社会效益。免疫策略为控制其它疫苗相关疾病提供了宝贵经验。
Objective To analyze the immunization strategies and effects in different stages of poliomyelitis eradication in Sanya City (hereinafter referred to as polio), and to provide experience in eliminating and controlling other vaccine-related diseases. Methods To collect the immunization strategies adopted in different stages and analyze the effects after implementation. Results The effects of different immune stages were different, and the effect of eliminating polio stage immunization strategy was the most significant. The routine immunization rate of poliovirus sustained over 85%, and the average of 22 rounds of immunization coverage reached more than 95%. The annual incidence of poliovirus in population antibody showed a continuous downward trend at 1: 400 high immunization strategy. Monitoring system monitoring Data confirmed that after April 1993 in Sanya City, 8 consecutive years without poliovirus infection occurred. Polio-free state to achieve the city. Since the eradication of polio, the economic burden on families has been reduced by 15.33 million yuan to 83.9 million yuan, generating 12.34 million yuan to 66.69 million yuan. Conclusion Sanya City, through the implementation of polio immunization strategy, has reached the cycle of blocking poliovirus, which has produced significant economic benefits and huge social benefits. Immunization strategies provide valuable experience in controlling other vaccine-related diseases.