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目的观察三益注射液对大鼠实验性股骨头坏死的治疗作用。方法采用大鼠乳鼠髋关节过度荷重和长期大量使用激素导致股骨头坏死的实验模型,观察静脉注射三益注射液的治疗效果。结果三益注射液组大鼠股骨BMD、BMC含量,股骨湿重、干重、灰量,股骨骨强度和骨钢性均明显高于模型对照组;股骨头内毛细血管接近恢复正常水平分布,排列也较有规律。结论三益注射液能明显增加大鼠股骨BMD、BMC含量,改善股骨头骨膜上微循环。
Objective To observe the therapeutic effect of Sanyi injection on experimental femoral head necrosis in rats. Methods The experimental model of femoral head necrosis caused by overloaded rat hip joints and long-term massive use of hormones was used to observe the therapeutic effect of intravenous injection of Sanyi injection. Results The contents of BMD and BMC in femurs, femur wet weight, dry weight, ash content, femur bone strength and bone rigidity in Sanyi injection group were significantly higher than those in the model control group. Capillary blood in the femoral head was near normal level. The arrangement is also more regular. Conclusion Sanyi injection can significantly increase the content of BMD and BMC in the femur of rats and improve the microcirculation of femoral head membrane.