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目的研究胃间质瘤的病理特点与临床诊治方法。方法回顾性分析32例胃间质瘤的临床和病理相关资料。结果全部病例均经手术治疗并经病理检查及免疫组化证实;其中瘤径>10cm的15例,瘤径<10cm的17例,5年生存率分别为47.4%和89.3%(P<0.05);对其中3种手术方式的5年生存率分别进行两两比较,差别无统计学意义(P均>0.05)。20例(83.3%)患者接受淋巴结清扫或活检,但仅1例发现转移。结论胃间质瘤术前确诊率低,临床诊断有赖于病理及免疫组化;手术切除为主要治疗方法,需保证足够的切缘,但扩大切除术对预后并无影响。
Objective To study the pathological features and clinical diagnosis and treatment of gastric stromal tumors. Methods The clinical and pathological data of 32 cases of gastric stromal tumors were retrospectively analyzed. Results All the cases were confirmed by pathological examination and immunohistochemistry. Among them, 15 cases with tumor diameter> 10 cm and 17 cases with tumor diameter <10 cm had 5-year survival rates of 47.4% and 89.3%, respectively (P <0.05) The 5-year survival rates of the three surgical methods were compared with each other, the difference was not statistically significant (P all> 0.05). Twenty patients (83.3%) underwent lymph node dissection or biopsy, but only one case found metastasis. Conclusion Preoperative diagnosis of gastric stromal tumors is low, the clinical diagnosis depends on the pathology and immunohistochemistry; surgical excision as the main treatment, to ensure adequate margins, but the expansion of excision has no effect on prognosis.