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目的:预防静脉滴注奥沙利铂所致的肢体麻木。方法:62例癌症患者静脉滴注奥沙利铂,随机分为干预组和对照组。对照组41例采用50%葡萄糖加25%硫酸镁、维生素B12的混合液,在静脉滴注奥沙利铂前用纱布湿敷;干预组21例在混合液的基础上再加地塞米松成为葡萄糖复合液,用同样的方法湿敷。结果:干预组的麻木程度、麻木时间远低于对照组,疗效明显高于对照组。结论:采用葡萄糖复合液能有效预防奥沙利铂所致肢体麻木。
Objective: To prevent limb numbness caused by intravenous oxaliplatin. Methods: Sixty-two cancer patients received intravenous infusion of oxaliplatin and were randomly divided into intervention group and control group. Control group, 41 cases of 50% glucose plus 25% magnesium sulfate, vitamin B12 mixture, intravenous infusion of oxaliplatin before gauze wet compress; intervention group, 21 patients on the basis of the mixture plus dexamethasone as glucose Complex solution, wet the same way. Results: The degree of numbness and numbness in the intervention group were much lower than those in the control group, and the curative effect was obviously higher than that in the control group. Conclusion: Glucose compound liquid can effectively prevent limb numbness caused by oxaliplatin.