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目的:探讨厄贝沙坦辅助治疗心力衰竭并心律失常的效果及对心功能的影响。方法:将我院收治的60例心力衰竭并心律失常患者随机分为2组,30例予以胺碘酮治疗(对照组),30例予以胺碘酮联合厄贝沙坦治疗(研究组)。比较两组患者临床疗效以及左室射血分数(LVEF)、左心室收缩末期内径(LVESD)、每搏心输出量(SV)及左心室舒张末期内径(LVEDD)。结果:研究组临床总有效率(96.67%)较对照组(73.33%)显著要高(P<0.05)。研究组患者LVEF、SV较对照组显著要低,LVEDD、LVESD较对照组显著要高(P<0.05)。结论:在心力衰竭并心律失常治疗中选择胺碘酮联合厄贝沙坦具有良好疗效,可令患者心功能显著改善,临床应用疗效确切。
Objective: To investigate the effect of irbesartan in the treatment of heart failure with arrhythmia and its influence on cardiac function. Methods: Sixty patients with heart failure and arrhythmia admitted to our hospital were randomly divided into two groups. 30 patients were treated with amiodarone (control group) and 30 patients received amiodarone combined with irbesartan (study group). The clinical efficacy, LVEF, LVESD, SV and LVEDD were compared between the two groups. Results: The total clinical effective rate (96.67%) in the study group was significantly higher than that in the control group (73.33%) (P <0.05). The LVEF and SV in study group were significantly lower than those in control group, LVEDD and LVESD were significantly higher than those in control group (P <0.05). Conclusion: Amiodarone combined with irbesartan in the treatment of heart failure and arrhythmia has a good curative effect, which can significantly improve the cardiac function and clinical curative effect.