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目的了解北京市朝阳区常住人口乙型病毒性肝炎(乙肝)病毒血清标志物流行情况。方法按照多阶段整群随机抽样的方法,抽取北京市朝阳区常住人口(居住6个月及以上)家庭中1~70岁人群,调查问卷同时采集静脉血3~5 ml进行乙肝三项检测。结果完成调查13 229人,HBs Ag阳性率为2.68%(354/13 229)(标化率2.37%)、HBs Ab阳性率47.05%(6 230/13 229)。北京市户籍人群HBs Ag和HBs Ab阳性率(2.20%;44.54%)均低于外地户籍人群(3.51%;51.51%)。乡村居住人群HBs Ab阳性率(44.91%)低于城市居住人群(48.91%)。男性HBs Ag和HBs Ab阳性率(3.15%;48.85%)均高于女性HBs Ag阳性率(2.36%;45.93%)。随调查人群年龄上升,HBs Ag阳性率逐渐上升,HBs Ab阳性率逐渐下降。15岁及以下儿童中乙肝疫苗调查接种率为98.13%,15岁以上人群乙肝疫苗调查接种率为38.66%。结论北京市朝阳区35岁以下人群HBs Ag阳性率较低,35~45岁人群HBs Ag阳性率较高并且乙肝疫苗接种率较低,提示我们需要加强35~45岁人群乙肝防控工作。
Objective To understand the prevalence of serological markers of hepatitis B virus (HBV) in resident population in Chaoyang District of Beijing. Methods According to the multistage cluster random sampling method, the population of 1-70 years old resident in the resident population (living in 6 months and above) in Chaoyang District of Beijing was sampled, and 3 to 5 ml of venous blood was also collected for the three tests of hepatitis B in the questionnaire. Results A total of 13 229 HBsAg-positive patients were investigated. The positive rate of HBsAg was 2.68% (354/13 229) (2.37%). The positive rate of HBs Ab was 47.05% (6 230/13 229). The positive rates of HBs Ag and HBs Ab in Beijing registered permanent residents (2.20% and 44.54%) were lower than those in other cities (3.51% and 51.51% respectively). The positive rate of HBs Ab in rural residents was lower than that in urban residents (44.91%) (48.91%). The positive rates of HBs Ag and HBs Ab in males (3.15% and 48.85%) were higher than those in females (2.36% and 45.93%, respectively). As the age of the investigated population increased, the positive rate of HBsAg gradually increased and the positive rate of HBsAb gradually decreased. The vaccination rate of hepatitis B vaccine in children aged 15 and below was 98.13%, and the vaccination rate of hepatitis B vaccine in people over 15 years old was 38.66%. Conclusions The positive rate of HBsAg in people under 35 years of age in Chaoyang district, Beijing is lower than that in people aged 35-45 years. The positive rate of HBsAg in people aged 35-45 years and the low vaccination rate of hepatitis B vaccine suggest that we need to strengthen the prevention and control of hepatitis B in people aged 35-45 years.