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近年研究证实由氧自由基介导的自由基连锁反应是急性脑梗死 (ACI)的核心病理环节，缺血后血液再灌流可使自由基连锁反应激化，造成严重的迟发性神经功能损伤。本研究采用 ESR结合快速低温冷冻技术直接测定 62例 ACI患者治疗前后全血自由基净含量，同时观察不同给药途径对其影响
In recent years, it has been confirmed that free radical chain reaction mediated by oxygen free radicals is the core pathological stage of acute cerebral infarction (ACI). Reperfusion after ischemia can intensify the free radical chain reaction and cause serious delayed neurological damage. In this study, the ESR combined with rapid cryogenic freezing technique was used to directly determine the net free radical content in 62 patients with ACI before and after treatment, and to observe the effect of different routes of administration