【摘 要】
:
The present study aims to analyze sperm concentration trends among young and healthy Chinese adults in Wuhan,Central China,from 2010 to 2015.Semen analysis data from 9357 participants were collected and analyzed using a general linear model and the Cochra
【机 构】
:
Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Techn
论文部分内容阅读
The present study aims to analyze sperm concentration trends among young and healthy Chinese adults in Wuhan,Central China,from 2010 to 2015.Semen analysis data from 9357 participants were collected and analyzed using a general linear model and the Cochran-Armitage trend test.A significant decline was observed in sperm concentration (β [standard deviation]:-1.53 [0.16];P < 0.001).In addition,a decline in sperm density was observed by stratifying student versus nonstudent sperm donors and by analyzing the year of birth or birth year cohort of the participants.Furthermore,the percentage of participants with sperm densities of over 40 × 106 ml-1 significantly decreased with year.Notably,a dramatic decline in sperm density was recorded over the first 5 years of study.This research reported a decline in sperm concentration among young adults in Wuhan,Central China,in 2010-2015.
其他文献
Stem cell therapy is a potentially promising option for erectile dysfunction; however, its risk of tumorigenicity is a clinical hurdle and the risk is positively related to the number of injected cells. Our previous study showed that nanotechnology improv
Prostate cancer (PCa) is a major health risk for older men worldwide.Existing systemic therapies mostly target androgen receptor (AR).Although treatments are initially effective,the disease always recurs.A potential mechanism for the treatment failure is
Dear Editor,rnIn its latest edition, the World Health Organization (WHO) provides guidelines regarding the standardization of techniques for the measurement of sperm concentration and recommends use of a 100 μm-deep hemocytometer. However, these instructi
Many studies have shown that microRNAs (miRNAs) play vital roles during the spermatogenesis.However,little is known about the altered miRNA profiles of testicular tissues in nonobstructive azoospermia (NOA).Using microarray technology,the miRNA expression
To investigate whether transcription of hepatitis B virus (HBV) gene occurs in human sperm,total RNA was extracted from sperm of patients with chronic HBV infection (test-1),from donor sperm transfected with a plasmid containing the full-length HBV genome
This study aimed to investigate perceived ejaculatory function/satisfaction before treatment for lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) and to identify associations between specific categories of ejaculatory dysfunctions (E
In the setting of an infected inflatable penile prosthesis (IPP),removal of the reservoir is a surgical challenge.We describe a novel technique for IPP reservoir removal at the time of IPP explantation utilizing laparoscopic instruments.We present two cas
Dear Editor,rnCarriers of balanced chromosomal rearrangements,including reciprocal,robertsonian translocations,and inversions,have all genetic information conserved.Nevertheless,because of the possibility of defect in chromosome segregation during gametog
Erectile dysfunction (ED) is a common disorder characterized by multifactorial etiology.Cardiovascular disease,diabetes,hormone alterations,and surgical manipulation represent the common causes of ED.1 Age is also an independent risk factor for ED,with an
Low testosterone (T) is frequent in men with chronic illnesses.The clinical features of T deficiency (TD) overlap with those of chronic diseases.The aim of this study is to evaluate the relative contribution of chronic disease score (CDS) and low T to the