血友病是一组常见的遗传性出血性疾病,包括血友病甲(Ⅷ因子缺陷症,典型血友病)、血友病乙(Ⅸ因子缺陷症、PTC缺陷症、Christmas病)和血友病丙(Ⅺ因子缺陷症、PTA缺陷症)。本病的发病率,以10万男性人口计算,美国为10.0～18.0,巴西14.0,英国12.0,瑞典11.0,日本10.4,非洲5.0。血友病甲、乙、丙的发病率约为16:3:1。典型病例的诊断虽不难,但反复出血和关节畸形等给患者和社会带来很大负担。近年来,对血友病的认识,有了很大进展,为血友病患者能正常生活和工作 Hemophilia is a common group of hereditary hemorrhagic diseases including hemophilia A (factor VIII deficiency, haemophilia), hemophilia B (factor IX deficiency, PTC deficiency, Christmas disease) and blood Friendly disease C (factor Ⅺ deficiency, PTA deficiency). The incidence of this disease, with a population of 100,000 males, is 10.0 to 18.0 in the United States, 14.0 in Brazil, 12.0 in the United Kingdom, 11.0 in Sweden, 10.4 in Japan and 5.0 in Africa. The incidence of hemophilia A, B, C is about 16: 3: 1. Although the diagnosis of typical cases is not difficult, but repeated bleeding and joint deformities and other patients and society to bring a heavy burden. In recent years, there has been great progress in understanding hemophilia, which enables people with hemophilia to live and work normally