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目的探析卡贝缩宫素+益母草注射液联合用药治疗行剖宫产术且具有高危产后出血因素产妇宫缩乏力性产后出血的临床治疗效果及意义。方法分析2015年5月-2016年4月在医院住院行剖宫产术的90例待产妇的临床资料,采用计算机随机生产数字法将入选者分为治疗组和对照组各45例。对照组剖宫产后宫体注射缩宫素,治疗组剖宫产后宫体注射卡贝缩宫素和臀部肌肉注射益母草注射液,比较两组产妇的基线资料、产后2 h及24 h的出血量、产后24 h血红蛋白(Hb)下降值以及不良反应发生率。结果两组产妇的基线资料差异无统计学意义(P>0.05)。治疗组产后2、24 h出血量以及24 h Hb下降值均明显低于对照组,差异有统计学意义(P<0.01),但两组产妇的产时出血量差异无统计学意义(P>0.05)。两组产妇的不良反应发生率差异无统计学意义(P>0.05)。结论具有高危产后出血因素的剖宫产者采用卡贝缩宫素+益母草注射液治疗可以获得较为理想的治疗效果,具有临床推广意义。
Objective To investigate the curative effect and significance of combined treatment of carbetocin and motherwort injection for cesarean section with high risk of postpartum hemorrhage due to postpartum hemorrhage. Methods The clinical data of 90 cases of expectant mothers undergoing cesarean section in hospital from May 2015 to April 2016 were analyzed. The randomized digital method was used to divide 45 patients into treatment group and control group. Control group cesarean postpartum oxytocin injection, the treatment group after cesarean section intrauterine injection of carbetocin and gluteal muscle injection of Motherwort, compared two groups of maternal baseline data, postpartum 2 h and 24 h of bleeding , Postpartum 24 h hemoglobin (Hb) decline and the incidence of adverse reactions. Results There was no significant difference in baseline data between the two groups (P> 0.05). The amount of hemorrhage and the value of 24 h Hb postpartum in treatment group were significantly lower than those in control group (P <0.01), but there was no significant difference in the amount of hemorrhage between the two groups (P> 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Cesarean section with high-risk postpartum hemorrhage factors can be treated with carbetocin and motherwort injection to achieve better therapeutic effect, which has clinical significance.