论文部分内容阅读
目的 :探讨糖尿病 (DM )患者血清Ⅳ型胶原 (CI IV)水平及其与各种慢性并发症的关系。方法 :69例糖尿病患者及 19例健康人用酶联免疫法测定血清CI IV水平。结果 :糖尿病组CI IV明显高于正常对照组 ,且有并发症者增高更明显。结论 :糖尿病患者血清CI IV水平升高 ,并与慢性并发症有关 ,故CI IV可作为反映微血管病变的早期指标。
Objective: To investigate the serum level of type Ⅳ collagen (CI IV) in patients with diabetes mellitus (DM) and its relationship with various chronic complications. Methods: Serum CI IV levels were measured by enzyme-linked immunosorbent assay in 69 patients with diabetes mellitus and 19 healthy people. Results: CI IV in diabetic group was significantly higher than that in normal control group, and complication increased more obviously. Conclusion: Serum CI IV levels in patients with diabetes mellitus are elevated and are related to chronic complications. Therefore, CI IV can be an early indicator of microvascular disease.