尾加压素Ⅱ (ｕｒｏｔｅｎｓｉｎⅡ ,ＵⅡ )最早是从鱼尾部神经下垂体中提取出的神经肽 ,近年已从人体脊髓中克隆出来。Ａｍｅｓ等在《Ｎａｔｕｒｅ》(1999,40 1:2 82 2 86 )上首次报道 ,ＵⅡ也分布于心血管组织 ,其血管收缩作用为内皮素的 10余倍 ,是迄今已知的最强的缩血管 Urotensin Ⅱ (UⅡ), the earliest neuropeptide extracted from the pituitary gland of fish, has been cloned from human spinal cord in recent years. Ames et al., “Nature” (1999, 40: 82 82 86) for the first time reported that, U Ⅱ also distributed in cardiovascular tissue, the vasoconstriction of endothelin is more than 10 times, is by far the strongest known shrinkage Blood vessels