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目的：通过研究以确定已报道的３种Ｈｐ快速诊断方法的适用范围。方法：以细菌培养法为标准，对快速尿素酶试验、ＩｇＧ抗体测定和ＰＣＲ法诊断Ｈｐ感染进行了比较研究。结果：快速尿素酶试验对Ｈｐ的阳性检出率与培养法差别不显著。ＰＣＲ法和抗体测定法阳性检出率高于培养法，两法特异性较低，敏感性和阴性预测性高。结论：快速尿毒酶试验价格低廉，操作简便、快速，可在临床推广应用；ＰＣＲ法适合于快速尿素酶试验阴性患者排除Ｈｐ感染的检验；抗体测定法标本易得，适合于大规模人群普查。
OBJECTIVE: To determine the applicability of three reported rapid Hp diagnostic methods. Methods: Bacterial culture method was used as a standard to compare rapid urease test, IgG antibody test and PCR to diagnose Hp infection. Results: Rapid urease test Hp positive detection rate and culture method difference was not significant. PCR and antibody assay positive detection rate is higher than the culture method, the two methods of low specificity, sensitivity and negative predictive high. Conclusion: The rapid urease test is cheap, simple, rapid and can be widely applied in clinic. PCR is suitable for the test of eliminating Hp infection in patients with negative urease test. The antibody assay is suitable for large-scale population screening.