背景和目的 Rh血型系统的遗传由RHD和RHCE基因控制,其分别编码RhD和RhCcEe多肽。两组基因中发生缺失、点突变或者基因重组造成该系统的高度遗传多态性。本研究目的在于分析Dc-表型的遗传基础。材料和方法 Dc-表现者及其家族成员的DNA样品乃从获得的周围血中制得。通过聚合酶链 Background and Objective The inheritance of the Rh blood group system is controlled by the RHD and RHCE genes, which encode RhD and RhCeEe polypeptides, respectively. Two sets of gene deletions, point mutations or genetic recombination caused by the system of high degree of genetic polymorphism. The purpose of this study was to analyze the genetic basis of the Dc-phenotype. Materials and Methods DNA samples of Dc-performers and their family members were prepared from the obtained peripheral blood. Through the polymerase chain