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目的观察维地洛治疗小儿扩张型心肌病(DCM)的临床疗效。方法将我院2010年1月-2012年1月收治的小儿扩张型心肌病患者90例随机分为观察组与对照组各45例,均接受地高辛、利尿剂及血管转换酶抑制剂治疗1个月以上,同时给予观察组卡维地洛片治疗,给予对照组倍他乐克片治疗,对比6个月后两组心率、左心室收缩期及舒张期内径、射血分数以及短轴缩短率。结果治疗6个月后观察组心率明显较对照组改善,左心室收缩期及舒张期内径明显较对照组缩短,射血分数以及短轴缩短率明显较对照组降低,各项目组间差异均有统计学意义(P<0.05)。结论卡维地洛治疗小儿扩张型心肌病疗效显著,值得临床推广使用。
Objective To observe the clinical efficacy of videoproxil in the treatment of children with dilated cardiomyopathy (DCM). Methods 90 patients with dilated cardiomyopathy in our hospital from January 2010 to January 2012 were randomly divided into observation group and control group, 45 cases each received digoxin, diuretic and angiotensin converting enzyme inhibitor 1 month, while giving the observation group of carvedilol tablets treatment, giving the control group metoprolol treatment, compared 6 months after the two groups heart rate, left ventricular systolic and diastolic diameter, ejection fraction and short axis Shorten the rate. Results After 6 months of treatment, the heart rate of the observation group was significantly improved compared with that of the control group. The left ventricular systolic and diastolic diameters were significantly shorter than those of the control group. The ejection fraction and short axis shortening rate of the observation group were significantly lower than those of the control group Statistical significance (P <0.05). Conclusion Carvedilol treatment of children with dilated cardiomyopathy significant effect, worthy of clinical promotion.