报道了 Ｐｆｉｔｚｉｎｇｅｒ 喹啉合成法在卓艹 酚酮领域中的首次应用． ３乙酰基卓艹酚酮（Ⅰ）在氢氧化钾存在下与靛红反应，得到了喹啉基取代的卓艹 酚酮化合物 ３［（４′羧基）２′喹啉基］卓艹 酚酮（Ⅱ）；化合物Ⅱ的溴化反应得到双溴代产物 ５，７二溴３［（４′羧基）２′喹啉基］卓艹 酚酮（Ⅲ）；化合物Ⅱ的偶氮偶联反应得到 ５ 位偶氮偶联产物５苯偶氮基３［（４′羧基）２′喹啉基］卓艹 酚酮（Ⅳ）．化合物Ⅱ、Ⅲ、Ⅳ为尚未见文献报道的新化合物，它们的结构已经红外光谱、核磁共振谱及元素分析予以证实． The first application of the Pfitzinger quinoline synthesis method in the field of zoran phenol was reported. 3  acetyl acyl phenol ketone (Ⅰ) in the presence of potassium hydroxide and isatin, quinolinyl substituted quinolone compounds 3  [(4’-carboxyl)  2’-quinolyl ] Zhuo Piolone ketone (II); Bromination reaction of compound II to get brominated product 5,7 dibromo  3  [(4’-carboxy)  2’-quinolyl] ); Azo coupling reaction of compound II to obtain 5 azo coupling products 5-phenylazo  3  [(4  carboxyl  2  quinolyl] Zhuo 艹 phenol ketone (Ⅳ). Compounds Ⅱ, Ⅲ and Ⅳ are new compounds which have not been reported in the literature and their structures have been confirmed by IR, 1HNMR and elemental analysis.