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比较维持性血液透析患者口服和静脉补铁治疗肾性贫血的疗效。方法将40例病情稳定的血液透析患者随机分成口服组和静脉组各20例,口服组口服福乃得(含硫酸亚铁525 mg),1片/d,静脉组输注右旋糖酐氢氧化铁(科莫非),每次100mg,每周2次,共10次后每2周给予维持量100mg,2组疗程均为9wk,观察治疗前后2组血红蛋白(Hb)、红细胞压积(Hct)、血清铁蛋白(SF)及转铁蛋白饱和度(TSAT)的变化。结论CRF贫血患者静脉补铁优于口服补铁。
To compare the therapeutic effects of oral and intravenous iron therapy on renal anemia in maintenance hemodialysis patients. Methods Forty patients with stable hemodialysis were randomly divided into oral and intravenous groups of 20 patients. The oral group was given Fuorishan (containing 525 mg of ferrous sulphate) and 1 / d intravenous infusion of iron dextran (100 mg twice a week for 10 times). The maintenance dose was 100 mg every 2 weeks. The duration of treatment was 9 weeks. The levels of hemoglobin (Hb), hematocrit (Hct), serum Ferritin (SF) and transferrin saturation (TSAT) changes. Conclusion Intravenous iron supplementation in patients with CRF anemia is superior to oral iron supplementation.