【摘 要】
:
Evidence for the existence of mon-keys with spontaneous Parkinson's disease(PD)has been lacking.Here,we screened macaque colonies at the Kunming Primate Researc
【机 构】
:
Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences&Yunn
论文部分内容阅读
Evidence for the existence of mon-keys with spontaneous Parkinson's disease(PD)has been lacking.Here,we screened macaque colonies at the Kunming Primate Research Center(Association for Assessment and Ac-creditation of Laboratory Animal Care(AAALAC)accredited),Kunming In-stitute of Zoology,Chinese Academy of Sciences,which has a large population of monkeys(>2400),to identify naturally occurring PD monkeys.Sixty cynomol-gus macaques and rhesus macaques with no experimental experience,housed in single cages of the Kunming Primate Research Center,were selected as the subjects of a preliminary screen proce-dure to search for naturally occurring PD(Supplementary Fig.S1).The subjects'age,gender and species information are listed in Supplementary Table S1.
其他文献
International collaboration has a long tradition amongst chemists worldwide, and I will take the liberty of starting with a personal note.My scientific forefath
目的 分析冯五金教授治疗反流性食管炎(reflux esophagitis,RE)的用药规律并总结治疗经验.方法 选取178例于2019年1月—2019年12月在山西省中医院冯五金专家门诊就诊的RE患者
目的 研究探讨补肾益智活血汤联合阿立哌唑治疗老年精神分裂症的疗效观察及对脑损伤标志物水平的改善.方法 选择2017年2月-2019年2月在医院接受治疗的120例精神分裂症患者分
The lower mantle, ranging from 660 to 2891 km in depth, comprises the vast majority of Earth's volume.Although the Earth's lower mantle has been regarded as com
崩漏是妇女非周期性的不规则性的阴道下血现象,或量大如注,或淋漓不断,是妇科临床上常见的、多发的疾病之一.中医药治疗此病独具特色,取得显著的成果,通过对血瘀型崩漏的诊疗
目的 研究川芎嗪注射液联合尼麦角林对急性脑梗死患者的治疗效果及血清学指标水平的影响.方法 选取2019年10月-2020年6月医院收治的86例急性脑梗死患者分为两组,各43例.对照
英语写作作为英语四大技能中的一种输出性技能,在英语教学中扮演着不可估量的角色.经过长期的写作训练,学生能够对输入性信息进行有效输出,实现对输入性知识的灵活运用,将输
构音障碍为脑卒中后最常见的交流障碍之一,使患者失去了正确表达单词的能力和交流能力,降低了患者的生活质量.以构音障碍为主题在中国知网(CNKI)数据库进行相关文献检索,选取
It is my honour to have been invited to contribute, on behalf of the Royal Society of Chemistry (RSC), to this important topical issue on International Chemistr
功能性胃肠病(functional gastrointestinal disorders,FGIDs)是以慢性或反复发作的胃肠道症状为临床表现,而无器质性病变的消化系统常见疾病.我国以功能性消化不良(function