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隐球菌病(cryptococcosis)是一种重要的世界性人兽共患的感染性真菌病,可侵犯人体的肺、脑、皮肤、骨骼等全身各脏器。因其强烈的嗜中枢性,所致的隐球菌性脑膜炎/脑膜脑炎(cryptococca meningitis/meningoencephalitis,CME)约占隐球菌感染的80%以上,具高病死率。现从流行病学、临床表现、实验室诊断及治疗几方面阐述隐球菌病诊治方面的进展。
Cryptococcosis is an important cosmopolitan infectious fungal disease that can invade the body’s organs such as the lung, brain, skin and bone. Due to its strong centrality, cryptococcal meningitis / meningoencephalitis (CME) accounts for more than 80% of cryptococcal infections and has a high case-fatality rate. Now from epidemiology, clinical manifestations, laboratory diagnosis and treatment of several aspects of cryptococcal diagnosis and treatment progress.