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目的了解医院住院患者多重药耐药菌感染现状及临床分布特征,为临床合理使用抗菌药物提供依据。方法利用实验室信息系统(LIS)和查看病人,对某县级综合性医院住院患者多重耐药菌感染情况进行了调查与分析。结果该医院在两年时间内,从住院患者送检标本中共检出病原菌2 308株,其中有1 334株为多重耐药菌株,占57.80%。在检出的鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌等菌株中,多重耐药菌株占50%以上,多重耐药菌感染的患者主要分布于重症监护病房、呼吸科和神经内科。多重耐药菌感染的患者,在医院获得感染占64.75%,社区获得感染占56.11%。结论该医院住院患者送检标本中检出的病原菌中,多重耐药菌比例较高,应加强细菌耐药性的监测和抗菌药物使用管理。
Objective To understand the current status and clinical distribution of multiple drug-resistant bacterial infections in hospitalized inpatients and provide the basis for rational use of antibacterials in clinical practice. Methods The laboratory information system (LIS) and patient examination were used to investigate and analyze the multi-drug resistant infections in inpatients in a county-level general hospital. Results A total of 2 308 pathogenic bacteria were detected from hospitalized patients during the two years. Among them, 1 334 strains were multidrug resistant, accounting for 57.80%. In the detected Acinetobacter baumannii, Klebsiella pneumoniae, Escherichia coli and other strains, multi-drug resistant strains accounted for more than 50%, multi-drug resistant bacteria infected patients are mainly distributed in the intensive care unit, respiratory and Neurology. In patients infected with multidrug-resistant bacteria, 64.75% were infected in the hospital and 56.11% were acquired in the community. Conclusion The prevalence of multidrug-resistant bacteria in the pathogenic bacteria detected in the inpatients of the hospital is higher than that of the multidrug-resistant bacteria. The monitoring of bacterial resistance and the management of antibacterials use should be strengthened.