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目的 :探讨癫发作间期脑血流变化对癫灶定侧的价值。方法 :4 7例癫病人发作间期行经颅多普勒超声脑血流速度测定 ,并与临床、脑电图定位和MRI/CT病灶对比分析。结果 :根据临床症状确定病灶侧的 19例病人中 ,病灶侧脑血流速度改变 (升高和降低 )的比率显著高于双侧脑血流速度对称者 ;在脑电图确定病灶侧的 2 4例病人中 ,病灶侧脑血流速度升高比率显著高于脑血流速度降低和双侧脑血流速度对称者 ;在MRI确定病灶侧的 13例病人中 ,病灶侧脑血流速度增快 7例 ,减慢 2例 ,双侧血流速度对称 4例。结论 :癫病人一侧脑血流速度增高 ,高度提示癫病灶侧。
Objective: To investigate the value of cerebral blood flow changes during epileptic seizure in epileptic seizure. Methods: The cerebral blood flow velocity of transcranial Doppler echocardiography in 47 epilepsy patients during the interictal period was determined and compared with clinical, EEG and MRI / CT lesions. RESULTS: Among the 19 patients with lesions on the lesion side determined by clinical symptoms, the rates of changes (increased and decreased) in the lesion side cerebral blood flow velocity were significantly higher than those with symmetrical bilateral cerebral blood flow velocities. On the lesion side 2 Among the 4 patients, the rate of increase of focal cerebral blood flow velocity was significantly higher than that of decreased cerebral blood flow velocity and bilateral cerebral blood flow velocity. Among the 13 patients with lesion side by MRI, the lesion side cerebral blood flow velocity increased Fast in 7 cases, slowed in 2 cases, bilateral blood flow velocity symmetry in 4 cases. Conclusion: Epilepsy patients with cerebral blood flow velocity increased, highly suggestive of epileptic lesions side.