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目的:研究地高辛环糊精包合物制备的方法.方法:用搅拌法制备地高辛环糊精包合物,UV、HPLC法测定其含量,结果:地高辛及其包合物的紫外吸收光谱完全一致.包合后地高辛的晶体衍射峰消失,差热分析检测同样说明包合后图谱的变化.结论:地高辛与环糊精包合成功.
OBJECTIVE: To study the preparation method of digoxin cyclodextrin inclusion complex.METHODS: The digoxin cyclodextrin inclusion complex was prepared by stirring method and its content was determined by UV and HPLC.Results: Digoxin and its inclusion compound The results of differential thermal analysis also showed the change of the spectrum after inclusion.Conclusion: The combination of digoxin and cyclodextrin is successful.