Combined effects of electroacupuncture and anti-depression drugs on the hippocampus and frontal lobe

来源 :Neural Regeneration Research | 被引量 : 0次 | 上传用户:mailxxf
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Electroacupuncture(EA) has been clinically used to treat depression and has resulted in favorable effects in China.However,results from animal studies and pathology do not reflect the influence of electroacupuncture treatment on in vivo physiological functions.To thoroughly and dynamically observe pathological changes during depression,the present study established EA + fluoxetine and fluoxetine groups to observe depression in patients.1H-magnetic resonance spectroscopy was utilized to determine the correlation between hippocampal frontal lobe metabolite changes and mental disorder scale.Results revealed significantly increased N-acetylaspartate(NAA)/creatine(Cr) in the bilateral hippocampus and right frontal lobe of depression patients treated with EA compared with fluoxetine.Changes in NAA/Cr in bilateral hippocampus and right frontal lobe in both groups,before and after treatment,negatively correlated with severity and curative effects.Choline/Cr changes in the bilateral frontal lobes of both groups were significant before and after treatment,but negatively correlated with curative effects.Choline/Cr changes in the bilateral hippocampus were significant in the EA + fluoxetine group before and after treatment,but negatively correlated with severity and the curative effects of depression.These results demonstrate abnormal biochemical metabolism in bilateral frontal lobes and hippocampus of depression patients,and show that EA significantly altered biochemical indices in the frontal lobes and hippocampus compared with fluoxetine. Has been clinically used to treat depression and has resulted in favorable effects in China. However, results from animal studies and pathology do not reflect the influence of electroacupuncture treatment on in vivo physiological functions. To thoroughly and distinctly observe pathological changes during depression, the present study established EA + fluoxetine and fluoxetine groups to observe depression in patients. 1H-magnetic resonance spectroscopy was utilized to determine the correlation between hippocampal frontal lobe metabolite changes and mental disorder scale. Results of significantly increased N-acetylaspartate (NAA) / creatine (Cr) in the bilateral hippocampus and right frontal lobe of depression patients treated with EA compared with fluoxetine. Change in NAA / Cr in bilateral hippocampus and right frontal lobe in both groups, before and after treatment, negatively correlated with severity and curative effects.Choline / Cr changes in the bilateral frontal lob es of both groups were significant before and after treatment, but negatively correlated with curative effects .Choline / Cr changes in the bilateral hippocampus were significant in the EA + fluoxetine group before and after treatment, but negatively correlated with severity and the curative effects of depression These results demonstrated abnormal biochemical metabolism in bilateral frontal lobes and hippocampus of depression patients, and show that EA significantly altered biochemical indices in the frontal lobes and hippocampus compared with fluoxetine.
其他文献
近年来 ,利用 2个激光束的激光焊接 ,或双束激光焊接 ,已经成为一种新兴的焊接技术。先前的研究表明 :利用双束激光工艺可以将焊瘤的起始延迟到较高速度下发生 ,并减缓冷却速
国家安全监管总局公布了《煤矿安全监察分局监察业务用房建设使用标准》和《煤矿安全监察车辆配备使用管理规定》,明确要求煤监系统不得向监察对象借款,不得接受监察对象的任
1975年11月30日,毛泽东接到高敬亭的女儿高凤英请求澄清父亲被害原因、作出结论的信。毛泽东指示有关部门重新审查,在有关高 On November 30, 1975, Mao Zedong received a
财税[2016]98号各省、自治区、直辖市、计划单列市财政厅(局)、国家税务局、地方税务局,新疆生产建设兵团财务局:经国务院批准,现就国家大学科技园(以下简称科技园)有关税收
本刊讯(记者陈惠)11月19日,广西召开专项会议,决定启动基层医疗卫生机构第二批实施国家基本药物制度暨综合改革试点工作。今年2月,广西部分基层医疗卫生机构开始实施国家基本
前不久,经黑龙江省省委、省政府决定,省编委下发《黑龙江省省直机关事务管理局职能设置、内设机构和人员编制规定》,组建黑龙江省省直机关事务管理局,负责省委、省人大、省政
各行署、拉萨市人民政府,自治区各委、办、厅、局: 为认真贯彻落实国务院《关于加强防震减灾工作的通知》(国发〔2004〕25号)精神,进一步加强防震减灾工作,切实保障人民群众
一些媒体在批评腐败现象时,总忘不了说“极少数人”、“极少数党员领导干部”、“极个别人”、“极个别地方”之类词语,似乎不这样说,便夸大了阴暗面,抹煞了光明面。而实际上,不管
01 艺术与资本的关系?rn答1:在主流市场上,经常可以见到它们在一起“玩”游戏.rn答2:艺术也可以和资本没关系,但当资本敲开艺术大门的时候,艺术是赤裸裸的.rn02 艺术创作中有
期刊
由于基层医院缺少诊治、监护危重新生儿的必要设备和技术力量,使危重新生儿院前急救及妥善转运工作越来越受到重视。本文将一年来在这方面的工作体会总结如下。 Due to the