杜仲皮具有补肝肾、强筋骨、安胎功能主治腰脊酸疼、足膝痿弱、小便余沥、阴下湿痒、胎漏欲坠;近代报导适用于高血压等。由于药源供应不足,临床上常用杜仲叶代替杜仲皮治病,並获得较好疗效。我们对两者在药理和化学分析方面作了一些对比性的实验观察,报告如下: 药理方面的比较实验材料:杜仲皮和叶由南京同仁堂制药厂提供,两者均为新鲜干燥之药材(Eucommia ulmoides oliv)。皮和叶均制成水煎剂和65％乙醇提取液(称“水煎剂”“醇提液”),两种样品的浓度都为1亳升(相当生药3克),分别供实验应用。实验方法与结果: 一、降血压作用方而的比较 (一) 对家兔血压的影响 1. 水煎剂:选择健康家兔5只,体重2.4—2.8kg,雌雄皆有,用乌拉坦(1g/kg)静脉注射麻醉后,按常规分离出颈动脉,描记颈动脉血压。皮和叶的水煎 Eucommia ulmoides has nourishing liver and kidney, strong bones and muscles, tocolytic function indicating lumbar vertebrae pain, foot and knee weakness, urine excess Lek, Yin wet itch, fetal leakage to fall; modern reports apply to high blood pressure. Due to the lack of supply of medicinal sources, Eucommia ulmoides leaves are often used in clinical practice instead of the treatment of eucommia bark, and better results have been obtained. We made some comparative experimental observations on the pharmacological and chemical analysis of the two, and the report is as follows: Pharmacological comparisons Experimental materials: The bark and leaves of Eucommia ulmoides were supplied by Nanjing Tongrentang Pharmaceutical Factory, both fresh and dried herbs (Eucommia Ulmoides oliv). The skin and leaves were made into water decoction and 65% ethanol extract (called “water decoction” and “alcohol extract”). The concentrations of both samples were 1 liter (equivalent to 3 grams of crude drug) for experimental applications. . Experimental methods and results: 1. Comparison of blood pressure lowering effects (I) Effect on rabbit blood pressure 1. Water decoction: Choose 5 healthy rabbits weighing 2.4-2.8 kg, male and female, with urethane ( After 1 g/kg intravenous anesthesia, the carotid arteries were routinely isolated and carotid blood pressure was recorded. Skin and leaf decoction