目的 :探讨治疗甲亢的新方法。方法 :在抗甲状腺药物治疗的基础上联合甲状腺内注射硬化剂和地塞米松与单纯使用抗甲状腺药物治疗的疗效进行比较。结果 :治疗 6周时观察甲亢症状基本消失者实验组为 3 9例 (75 % ) ,对照组 2 3例 (4 4.2 % ) ,P <0 .0 1。全部患者症状基本消失所需时间 ,实验组为 62 .2± 18.6d ,对照组 82 .2± 2 6.1d ,P <0 .0 1。结论 :抗甲状腺药物联合甲状腺内局部注射硬化剂和地塞米松治疗甲亢是一种简便、安全、有效的方法 Objective: To explore a new method of treating hyperthyroidism. Methods: Based on anti-thyroid drug therapy, the effect of combination of thyroid injection of sclerotherapy and dexamethasone with anti-thyroid drugs was compared. Results: At the 6th week of treatment, 39 cases (75%) in experimental group and 23 cases (4.2%) in control group had significant disappearance of symptoms of hyperthyroidism, P <0.01. The time required for the complete disappearance of symptoms in all patients was 62.2 ± 18.6 days in the experimental group and 82.2 ± 6.16 days in the control group, P <0.01. Conclusion: Antithyroid drugs combined with intrathyroidal local injection of sclerotherapy and dexamethasone in the treatment of hyperthyroidism is a simple, safe and effective method