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目的 评价无水酒精瘤内注射(PEIT)治疗原发性小肝癌的疗效。方法 采用B超普通探头引导下经皮肝穿刺瘤内注射无水酒精治疗经手术或病理证实的原发性小肝癌患者(肿瘤直径<3cm)240例,其中复发性肝癌163例,因心肺肝肾功能不全或因病灶靠近大血手术不能切除者55例,拒绝手术治疗者22例;46例患者本法治疗后手术切除肿瘤送病理检查观察肿瘤坏死情况,术后随访。结果 治疗后,240例患者1年,2年及3年生存率分别为94.9％,84.2％和 66.3％。结论 经皮肝穿刺无水酒精瘤内注射可作为原发性小肝癌一种非手术治疗方法,手术前PEIT可降低患者术后复发率。
Objective To evaluate the efficacy of non-alcoholic alcohol injection (PEIT) in the treatment of primary small hepatocellular carcinoma. Methods 240 patients with primary small hepatocellular carcinoma (tumor diameter <3cm) who underwent surgery or pathology were treated with intraperitoneal injection of anhydrous alcohol under the guidance of B ultrasound probe. There were 163 cases of recurrent hepatocellular carcinoma (HCC) Renal insufficiency or due to lesions near the blood can not be removed in 55 cases, 22 patients refused to surgery; 46 patients after surgical resection of the tumor to send pathological examination of tumor necrosis, follow-up after surgery. Results After the treatment, the 1-, 2- and 3-year survival rates of 240 patients were 94.9%, 84.2% and 66.3%, respectively. Conclusion Intraperitoneal injection of anhydrous alcohol into percutaneous liver tumor can be used as a non-surgical treatment of primary small hepatocellular carcinoma. Pre-operative PEIT can reduce postoperative recurrence rate.