新生儿缺氧缺血性脑病(HIE)是围生期窒息所致缺氧缺血性损害,是新生儿早期发病和死亡的重要原因。我院应用盐酸纳络酮辅助治疗新生儿缺氧缺血性脑病合并呼吸改变31例,效果显著,现报道如下:1　病例与方法1.1　病例选择我科1997年1月～1999年8月59例新生儿HIE患儿,诊断标准及临床 Neonatal hypoxic-ischemic encephalopathy (HIE) is hypoxia-ischemic damage caused by perinatal asphyxia and is an important cause of neonatal morbidity and mortality. Our hospital naloxone hydrochloride adjuvant treatment of neonatal hypoxic-ischemic encephalopathy with respiratory changes in 31 cases, the effect is remarkable, are reported as follows: 1 cases and methods 1.1 case selection our department from January 1997 to August 1999 59 cases Neonatal children with HIE, diagnostic criteria and clinical