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慢性胰腺炎是多种因素导致的胰腺组织和功能慢性进行性炎症性疾病,腺泡破坏,间质纤维化、胰管结石或扩张等是其主要病理表现。临床一般先表现为反复腹部及背部疼痛,继而表现为胰腺外分泌(消化、吸收障碍)及内分泌(糖耐量异常)不足。发病因素主要涉及胆道系统疾病、酒精中毒、遗传、自身免疫因素、热带性胰腺炎及特发性胰腺炎,机制并未明确。西医药物治疗的主要目的是抗氧化、抑制炎症因子,缓解疼痛,改善营养不良及脂肪泻等,中药方剂通过辨证施治、综合治疗,在防止发病,阻断进展,促进康复显示了独特作用。
Chronic pancreatitis is the main pathological manifestation of pancreatic tissues and function chronic progressive inflammatory diseases caused by many factors, acinar disruption, interstitial fibrosis, pancreatic duct stones or dilatation. The general clinical first showed repeated abdominal and back pain, followed by the performance of pancreatic exocrine (digestion and absorption disorders) and endocrine (impaired glucose tolerance) deficiencies. The main pathogenesis of biliary tract disease, alcoholism, genetic, autoimmune factors, tropical pancreatitis and idiopathic pancreatitis, the mechanism is not clear. Western medicine treatment of the main purpose is anti-oxidation, inhibition of inflammatory cytokines, relieve pain, improve malnutrition and steatorrhea, Chinese medicine prescriptions through syndrome differentiation, comprehensive treatment, prevention of disease, blocking progress and promoting rehabilitation show a unique role.