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目的:检测甲状腺功能亢进(简称甲亢)患者的心率变异性(heart rate variability,HRV),并探讨其临床意义。方法:对168例甲亢患者与200例同期体检正常人群(对照组)行24h动态心电图检查,观察下列指标:总体标准差(SDANN),均值标准差(SDNN),标准差均值(SDNN index),差值均分的平方根(RMSSD),以及VLF,LF,HF。甲亢组经131Ⅰ治疗6个月后复查24h动态心电。结果:甲亢组HRV各项指标均数较对照组显著降低,经131Ⅰ治疗后明显改善。结论:甲亢患者心脏自主神经功能损害,HRV降低,131Ⅰ治疗可改善HRV。
Objective: To detect heart rate variability (HRV) in patients with hyperthyroidism (Hyperthyroidism) and to investigate its clinical significance. Methods: A total of 168 patients with hyperthyroidism and 200 normal controls (control group) underwent 24 hours dynamic electrocardiogram examination. The following indexes were observed: SDANN, SDNN, SDNN index, Square root of difference (RMSSD), and VLF, LF, HF. Hyperthyroidism group by 131 Ⅰ after 6 months of review 24h dynamic ECG. Results: The average number of HRV in hyperthyroidism group was significantly lower than that in control group, and was significantly improved after 131 Ⅰ treatment. Conclusion: Autonomic nerve dysfunction and HRV in patients with hyperthyroidism decrease, and 131 Ⅰ treatment can improve HRV.