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目的研究分析美罗培南治疗急性白血病合并重症肺部感染的临床效果。方法 84例急性白血病合并重症肺部感染患者,随机分为对照组和观察组,各42例。对照组采用亚胺培南/西司他丁钠治疗,观察组采用美罗培南治疗。对比两组患者治疗总有效率、细菌清除率和不良反应发生情况。结果观察组治疗总有效率、细菌清除率及不良反应发生情况均优于对照组(P<0.05)。结论美罗培南治疗急性白血病合并重症肺部感染患者效果显著,可明显提高治疗有效率和细菌清除率,减少不良反应,值得推广。
Objective To study the clinical effects of Meropenem in the treatment of acute leukemia complicated with severe pulmonary infection. Methods A total of 84 acute leukemia patients with severe pulmonary infection were randomly divided into control group and observation group, with 42 cases in each group. The control group was treated with imipenem / cilastatin sodium and the observation group was treated with meropenem. The total effective rate of treatment, bacterial clearance and incidence of adverse reactions were compared between the two groups. Results The total effective rate of treatment, bacterial clearance rate and incidence of adverse reactions in the observation group were better than those in the control group (P <0.05). Conclusion Meropenem is effective in treating patients with acute leukemia complicated with severe pulmonary infection, which can significantly improve the treatment efficiency and bacterial clearance rate and reduce adverse reactions, which deserves promotion.