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岩藻糖基转移酶(Fucosyltransferases)使岩藻糖从鸟嘌吟核苷(GDP)岩藻糖转化至相应的糖蛋白或碳水化合物。原已发现在患肿瘤的动物和患新生物疾患的病人血浆内岩藻糖基移转酶值增高。酶值增高可能与膜的成分以及和膜结合的酶流入血浆有关,因为许多糖基转移酶同细胞表面的成分相结合,也可能涉及更特异的分泌过程。作者采用有校正内源性酶受体措施的方法来测定未经治疗、对化疗无反应和处于缓解期的急性粒细胞性白血病(下称急粒)病人血浆内两种岩藻糖基转移酶值。
Fucosyltransferases convert fucose from the guanosine (GDP) fucose to the corresponding glycoprotein or carbohydrate. It has been found that fucosyltransferase increases in the plasma of tumor-bearing animals and patients suffering from new biological disorders. Increased enzyme values may be related to membrane components and membrane-bound enzymes that flow into the plasma, as many glycosyltransferases bind to cell surface components and may also involve more specific secretion processes. The authors used a method of correcting endogenous enzymatic receptors to measure two fucosyltransferases in the plasma of untreated, unresponsive, and relapsing patients with acute myelogenous leukemia (hereinafter referred to as acute granules). value.