目的探讨纳洛酮与以氨茶碱为主的呼吸衰竭(呼衰)合剂在抢救新生儿呼吸衰竭中的疗效。方法 95例患儿采用随机对照研究,比较纳洛酮与氨茶碱治疗呼吸衰竭的近期疗效。结果纳洛酮组治疗呼吸衰竭有效率为96.1%,以氨茶碱为主组成的呼衰合剂组治疗呼吸衰竭有效率为79.3%,两组比较差异有统计学意义(P<0.05)。结论纳洛酮治疗呼吸衰竭疗效优于以氨茶碱为主组成的呼衰合剂。 Objective To investigate the efficacy of naloxone and aminophylline-based respiratory failure (respiratory failure) mixture in the rescue of neonatal respiratory failure. Methods Ninety-five children were randomized controlled study to compare the short-term efficacy of naloxone and aminophylline in the treatment of respiratory failure. Results The effective rate of naloxone group in treating respiratory failure was 96.1%. The effective rate of respiratory failure group treated with aminophylline was 79.3%. There was significant difference between the two groups (P <0.05). Conclusion Naloxone is superior to respiratory failure in treating respiratory failure.