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本文采用改良Ａｌｌｅｎ’ｓ法，分别以５０ｇ／ｃｍ和１００ｇ／ｃｍ打击大鼠Ｔ１３～Ｌ１脊髓，造成不同程度的脊髓损伤，分别观察伤后２４小时内的ＳｐＥＰ和ＣＭＥＰ的变化，以了解不同程度损伤对ＳｐＥＰ和ＣＭＥＰ的影响及ＳｐＥＰ、ＣＭＥＰ的变化与脊髓继发性损伤发展过程的关系。结果表明：①两种不同程度的脊髓损伤均可造成大鼠脊髓ＳｐＥＰ，ＣＭＥＰ的明显变化，尤以ＳｐＥＰ变化明显。损伤越重，电位改变越明显．②在脊髓损伤后１～２４小时内，伤后１０分钟ＳｐＥＰ，ＣＭＥＰ波幅却有明显降低，４～８小时进一步降低。两次降低有明显差异。ＳｐＥＰ峰潜伏时延长，以４～８小时显著。表明原发损伤后在受损部位存在继发性损伤，提示阻止继发损伤的时间应早于伤后４小时，并尽可能提前。
In this paper, improved Allen’s method was used to impact the spinal cord of rat T13 ~ L1 at 50g / cm and 100g / cm, respectively, resulting in different degrees of spinal cord injury. The changes of SpEP and CMEP within 24 hours after injury were observed respectively to understand the different degrees The effect of injury on SpEP and CMEP and the relationship between the changes of SpEP and CMEP and the development of spinal cord secondary injury. The results showed that: (1) Spinal cord injury at two different levels could cause significant changes of SpEP and CMEP in spinal cord, especially SpEP. The more damage, the more obvious changes in potential. ② Within 1 to 24 hours after spinal cord injury, the amplitude of SpEP and CMEP decreased significantly 10 minutes after injury and further decreased from 4 to 8 hours. There are significant differences between the two reductions. SpEP peak latency extended to 4 to 8 hours significantly. This indicates that there is secondary injury in the damaged area after primary injury, suggesting that secondary injury should be stopped earlier than 4 hours after injury and should be advanced as early as possible.