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目的:探讨不同品种芦荟对荷瘤小鼠体内肿瘤的押制作用及木立芦荟对5-Fu的增效减毒作用。方法:观察不同品种及浓度的芦荟对S180荷瘤小鼠的抑瘤率、脾系数、体重和H22荷瘤小鼠生存时间的影响;并以脾系数为指标,观察木立芦荟对5-Fu的增效减毒作用。结果:不同品种及浓度的芦荟对S180荷瘤小鼠的肿瘤均具有不同程度的抑制作用,延长H22荷瘤小鼠生存时间。木立芦荟可显著改善5-Fu引起的机体生理机能紊乱,提高其抑瘤作用。结论:芦荟具有较好的抗肿瘤及增效减毒药理作用。
Objective: To investigate the effect of different varieties of aloe on the tumor production in tumor-bearing mice and the synergistic and attenuating effects of Aloe arborescens on 5-Fu. METHODS: The effects of different concentrations and concentrations of aloe on the tumor inhibition rate, spleen coefficient, body weight, and survival time of H22 tumor-bearing mice in S180 tumor-bearing mice were observed. Spleen index was used as an indicator to observe the effects of Aloe arborescens on 5-Fu. Synergies and attenuating effects. RESULTS: Different varieties and concentrations of Aloe Vera had different degrees of inhibition on tumors in S180 tumor-bearing mice, prolonging the survival time of H22 tumor-bearing mice. Aloe arborescens can significantly improve the physiological function of 5-Fu caused by the body, and enhance its anti-tumor effect. Conclusion: Aloe vera has good anti-tumor and synergistic effects.