最近有研究表明,胰岛素可改善全脑缺血模型的脑损害。为探明胰岛素对局灶性脑缺血是否也有神经保护作用,我们在正常体温、血压8kPa条件下暂时闭塞30只大鼠大脑中动脉2h,其中20只在夹闭前给予2～3U/kg的胰岛素,10只不给胰岛素。为进一步阐明梗塞体积是否受生理范围内不同血糖水平的影响,给10只胰岛素组大鼠静注50％葡萄糖使血糖水平与 Recent studies have shown that insulin can improve brain damage in the global cerebral ischemia model. To find out whether insulin has neuroprotective effect on focal cerebral ischemia, we temporarily occluded 30 rats middle cerebral artery at normal temperature and blood pressure of 8kPa for 2h, of which 20 were given 2 ~ 3U / kg before clamping Of insulin, 10 do not give insulin. To further elucidate whether infarct volume is affected by different blood glucose levels in the physiological range, 10 insulin groups were intravenously injected with 50%