水中微溶性药物仅用一般水溶性介质，如人工胃液（SGF）、人工肠液（SIF）、水和缓冲液进行体外溶解实验是不合适的。表面活性剂、胆酸、胆盐和卵磷脂能增加微溶性药物的溶解速率，但价格较贵。本实验在溶解介质中加入少量合成的表面活性剂十二烷基硫酸钠（SLS），为微溶性药物 In vitro dissolution tests of sparingly soluble drugs in water using only common water-soluble media, such as artificial gastric juice (SGF), artificial intestinal juice (SIF), water and buffer, are unsuitable. Surfactants, bile acids, bile salts and lecithin increase the rate of dissolution of sparingly soluble drugs, but are more expensive. This experiment in the dissolution medium by adding a small amount of synthetic surfactant sodium lauryl sulfate (SLS), as a slightly soluble drug