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目的探讨复发性脑恶性胶质瘤患者的显微手术治疗效果。方法回顾性分析50例复发性脑恶性胶质瘤患者的临床资料。结果化疗及放疗对照组20例复发性脑恶性胶质瘤患者治疗后KPS评分改善3例,无明显变化11例,加重6例,平均55.50分,而显微手术治疗组的30例复发性脑恶性胶质瘤患者,术后KPS评分均有不同程度的改善,无手术相关死亡病例,平均71.67分,两组相比差异有统计学意义(P<0.05);对照组中位生存时间7个月,而治疗组中位生存时间13个月,后者显著高于前者(P<0.05)。结论复发性脑恶性胶质瘤显微手术治疗是提高患者生存质量、延长生存时间的主要手段,是后续治疗的基础。
Objective To investigate the effect of microsurgical treatment in patients with recurrent malignant glioma. Methods The clinical data of 50 patients with recurrent brain malignant glioma were retrospectively analyzed. Results In the chemotherapy and radiotherapy control group, the KPS scores of 20 patients with recurrent glioblastoma after treatment were improved in 3 cases, with no significant change in 11 cases and 6 cases with an average of 55.50 points, while in the microsurgical group, 30 cases of recurrent brain In patients with glioblastoma, the postoperative KPS scores improved to some extent, with no deaths associated with surgery, with an average of 71.67 points (P <0.05). The median survival time in the control group was 7 Month, while the median survival time of the treatment group was 13 months, which was significantly higher than the former (P <0.05). Conclusions The microsurgical treatment of recurrent glioblastoma is the main means to improve the quality of life and extend the survival time of patients, which is the basis of follow-up treatment.