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目的观察原发性高血压患者动态血压(ABMP)参数与颈动脉内膜中层厚度(IMT)、左室肥厚(LVH)、尿微量白蛋白(MA)的关系。方法178例原发性高血压患者行颈动脉超声。心脏超声心动图检查和尿微量白蛋白测定,同时行24h动态血压监测。将患者分为颈动脉IMT增厚组和非IMT增厚组,LVH组和非LVH组,MA阳性组和MA阴性组,比较两组的动态血压参数变化。结果两组血压参数比较:24h平均收缩压、24h平均舒张压、白天平均收缩压、白天平均舒张压、夜间平均收缩压、夜间平均舒张压、非勺形血压节律,各组数据比较均有显著性差异。结论高血压患者行ABMP,可以充分了解血压的情况和血压昼夜节律情况,对分析是否存在靶器官损害有一定的帮助,可为选择降压药物降低靶器官的损害提供有价值的检查。
Objective To investigate the relationship between ambulatory blood pressure (ABMP) parameters and carotid intima - media thickness (IMT), left ventricular hypertrophy (LVH) and urinary albumin (MA) in patients with essential hypertension. Methods 178 patients with essential hypertension underwent carotid artery ultrasound. Echocardiography and urine microalbuminuria were measured at the same time 24h ambulatory blood pressure monitoring. Patients were divided into carotid IMT thickening group and non-IMT thickening group, LVH group and non-LVH group, MA positive group and MA negative group. The changes of ambulatory blood pressure parameters were compared between the two groups. Results The blood pressure parameters of two groups were compared: 24h mean systolic pressure, 24h mean diastolic pressure, daytime mean systolic pressure, daytime mean diastolic pressure, nighttime average systolic pressure, nighttime mean diastolic pressure, non-spoon-shaped blood pressure rhythm, the data of each group were significantly Sex differences. Conclusions ABMP can fully understand the blood pressure and circadian rhythm of blood pressure in patients with hypertension. It is helpful to analyze the existence of target organ damage and provide valuable examination for selecting antihypertensive drugs to reduce the damage of target organs.