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目的观察热毒宁注射液联合葡萄糖酸锌治疗小儿肠炎的临床疗效。方法选取该院收治的肠炎患儿108例作为研究对象,遵循随机、均等原则分为观察组和对照组,每组54例。观察组给予热毒宁注射液联合葡萄糖酸锌治疗,对照组给予蒙脱石散联合阿莫西林颗粒治疗。对比观察2组临床疗效、临床症状消退时间、住院时间以及不良反应发生情况。结果观察组总有效率为88.89%显著高于对照组的75.93%,差异有统计学意义(χ2=4.267,P<0.05)。观察组患儿退热、止泻、纠正脱水、止吐时间以及住院时间显著低于对照组,差异均有统计学意义(P<0.05)。2组均未发生肝功能损伤、皮疹、胸闷等不良反应。结论热毒宁注射液联合葡萄糖酸锌可有效改善肠炎患儿临床症状,提高治疗效果,且安全性高。
Objective To observe the clinical efficacy of Renduining injection combined with zinc gluconate in the treatment of children with enteritis. Methods A total of 108 children with enteritis admitted to this hospital were enrolled in this study. According to the principle of randomization and equalization, 54 cases were divided into observation group and control group. The observation group was given Renduining injection combined with zinc gluconate, while the control group was treated with montmorillonite powder and amoxicillin granules. The clinical efficacy, clinical symptom subsidence time, hospitalization time and incidence of adverse reactions were compared between the two groups. Results The total effective rate of the observation group was 88.89%, which was significantly higher than that of the control group (75.93%, χ2 = 4.267, P <0.05). The observation group patients with fever, antidiarrheal, correct dehydration, antiemetic time and hospitalization was significantly lower than the control group, the difference was statistically significant (P <0.05). No adverse reactions such as liver function damage, skin rashes and chest tightness occurred in the two groups. Conclusion Reveduning injection combined with zinc gluconate can effectively improve the clinical symptoms of children with enteritis, improve the therapeutic effect, and high safety.