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目的比较两种方法治疗高龄高危大体积前列腺增生(BPH)合并膀胱大结石的疗效。方法选取高龄高危大体积BPH患者124例,随机分为研究组(62例)与对照组(62例),研究组行改良尿道腔内剜除术(M-PKEP)联合膀胱切开取石,对照组行经尿道前列腺电切术(TURP)联合钬激光碎石,对比分析两组患者在术中与术后的相关指标。结果研究组手术时间、术中出血量、术后膀胱冲洗时间低于对照组,前列腺切除质量、比例大于对照组,差异均有统计学意义(P<0.05)。两组术后前列腺症状评分、剩余尿量、最大尿流率水平均较术前改善,差异有统计学意义(P<0.05)。但术后研究组改善水平优于对照组,差异有统计学意义(P<0.05)。结论 M-PKEP联合膀胱切开取石治疗高龄高危大体积BPH合并膀胱大结石疗效显著,手术安全性高,并发症少。
Objective To compare the efficacy of the two methods in treating high-risk and large-volume benign prostatic hyperplasia (BPH) complicated with large urolithiasis in the elderly. Methods 124 elderly patients with high risk and large volume of BPH were randomly divided into study group (62 cases) and control group (62 cases). The study group was treated by modified urethral cavity excision (M-PKEP) Group transurethral resection of the prostate (TURP) combined with holmium laser lithotripsy, comparative analysis of the two groups of patients with intraoperative and postoperative related indicators. Results The operation time, intraoperative blood loss, postoperative bladder irrigation time were lower than that of the control group, the quality of prostatectomy, the proportion was greater than the control group, the difference was statistically significant (P <0.05). Prostate symptom scores, residual urine volume and maximum urinary flow rate in both groups were significantly improved compared with that before operation (P <0.05). However, postoperative improvement of the study group was better than the control group, the difference was statistically significant (P <0.05). Conclusions M-PKEP combined with cesarean section in the treatment of high-risk and large-volume BPH complicated with large urolithiasis has significant curative effect, high operative safety and few complications.