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目的探讨雾化吸入利多卡因治疗慢性喘息型支气管炎急性发作的临床疗效。方法入选符合标准的慢性喘息型支气管炎急性发作患者108例,将其按照治疗方式的不同分为两组,每组54例;对照组患者给予常规临床治疗,治疗组患者在对照组基础上加用雾化吸入利多卡因治疗;观察并分析两组患者的临床效果。结果两组患者药物治疗后,临床症状均有改善,但治疗组患者的CO2分压、动脉血压、最大呼吸量、第一秒钟用力呼气容积、心率及呼吸频率明显均优于对照组,差异均有统计学意义(均P<0.05)。结论慢性喘息型支气管炎急性发作患者在常规治疗的基础上加用雾化吸入利多卡因治疗,有效缓解了患者的临床症状,是临床较为理想的治疗方案。
Objective To investigate the clinical efficacy of inhaled lidocaine in the treatment of acute episode of chronic asthmatic bronchitis. Methods A total of 108 patients with acute asthmatic bronchitis were enrolled in this study. They were divided into two groups according to the different treatment methods, 54 cases in each group. The patients in the control group were given routine clinical treatment. The patients in the treatment group were added on the basis of the control group Inhaled lidocaine with nebulization; observed and analyzed the clinical effect of two groups of patients. Results After treatment, the clinical symptoms were improved in both groups. However, the CO2 partial pressure, arterial blood pressure, maximum respiration, forced expiratory volume in the first second, heart rate and respiration rate in the treatment group were significantly better than those in the control group. The differences were statistically significant (all P <0.05). Conclusion The patients with acute asthma exacerbation of acute asthmatic bronchitis are treated with atomized inhalation of lidocaine on the basis of routine treatment, which can effectively relieve the clinical symptoms of patients. Therefore, it is an ideal clinical treatment plan.