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目的分析纳美芬联合醒脑静对急性一氧化碳中毒高压氧治疗患者生存质量的影响。方法选取2015年2月-2016年5月我院收治的80例急性一氧化碳中毒患者,随机分为两组,各40例。对照组采用高压氧治疗,观察组在对照组治疗的基础上加用纳美芬联合醒脑静,对比两组治疗的临床疗效、治疗前后生存质量评分。结果观察组治疗有效率为90.00%,明显高于对照组72.50%,差异有统计学意义(P<0.05);治疗前,两组生存质量比较差异无统计学意义(P>0.05);治疗后,观察组心理、生理、社会、环境评分均高于对照组,差异有统计学意义(P<0.05)。结论纳美芬与醒脑静联合高压氧在治疗急性一氧化碳中毒中临床疗效显著,可缩短清醒时间,减少中枢神经系统的损伤,有助于患者生活质量的提高,值得临床推广应用。
Objective To analyze the effect of nalmefene combined with xingnaojing on the quality of life in patients with hypercapnic carbon monoxide poisoning. Methods From February 2015 to May 2016, 80 patients with acute carbon monoxide poisoning admitted to our hospital were randomly divided into two groups (n = 40 in each group). The control group was treated with hyperbaric oxygen. The observation group was treated with nalmefene combined with xingnaojing on the basis of the control group, and the clinical curative effect and the quality of life before and after treatment were compared. Results The effective rate of observation group was 90.00%, which was significantly higher than that of control group (72.50%), the difference was statistically significant (P <0.05). Before treatment, there was no significant difference in quality of life between the two groups (P> 0.05) The score of psychology, physiology, society and environment in the observation group were higher than those in the control group (P <0.05). Conclusions Nalmefene combined with xingnaojing combined with hyperbaric oxygen has significant curative effect in the treatment of acute carbon monoxide poisoning. It can shorten the awake time and reduce the damage of the central nervous system, which helps to improve the quality of life of patients and deserves clinical application.