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目的对中西医结合治疗2型糖尿病下肢动脉硬化闭塞症(ASO)的临床表现进行观察和分析。方法对目前26例ASO患者进行随机分组,分为对照组和观察组,每组各13例,在控制血糖、抗血小板聚集、调脂的基础上,对两组患者进行甲钴胺、硫辛酸、前列地尔静滴。观察组在除上述治疗中,加用中药熏蒸治疗,两组均治疗3周,最后对治疗效果、下肢溃疡发生率及血流动力学进行评价。结果观察组与对照组相比,总有效率更高(P<0.05);2组的溃疡发生率相比,差异无统计学意义(P>0.05);2组在足脊动脉峰值流速、足背动脉血流量、血小板聚集率及后踝肱指数上,治疗效果明显,有较大改善(P<0.05),因此可见,观察组与对照组相比,治疗效果更佳。结论对2型糖尿病下肢动脉硬化闭塞症患者采取中西医结合的治疗方法能有效改善其治疗效果和血流动力学.但对溃疡发生率起不到改善的作用。
Objective To observe and analyze the clinical manifestations of type 2 diabetic lower extremity arteriosclerosis obliterans (ASO) treated with integrated traditional Chinese and western medicine. Methods Twenty-six patients with ASO were randomly divided into control group and observation group, with 13 cases in each group. On the basis of controlling blood glucose, anti-platelet aggregation and lipid regulation, two groups of patients were treated with methylcobalamin, Prostatitis intravenous infusion. Observation group in addition to the above treatment, plus traditional Chinese medicine fumigation treatment, both groups were treated for 3 weeks, and finally the treatment effect, lower limb ulcer incidence and hemodynamic evaluation. Results Compared with the control group, the total effective rate was significantly higher in the observation group (P <0.05). There was no significant difference in the incidence of ulcer between the two groups (P> 0.05) Dorsal artery blood flow, platelet aggregation rate and posterior ankle brachial index, the treatment effect is obvious, there is a big improvement (P <0.05), therefore, the observation group compared with the control group, the treatment effect is better. Conclusion The treatment of type 2 diabetes patients with lower extremity arteriosclerosis obliterans with traditional Chinese medicine and western medicine can effectively improve the therapeutic effect and hemodynamics, but it can not improve the incidence of ulcer.