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目的:探讨人群中不规则抗体的阳性率及与临床安全输血的关系。方法:选取2012年2月至2015年2月在该院申请临床输血的患者15800例患者,对其采用微柱凝胶抗球蛋白法进行不规则抗体筛查。结果:1.15 800例患者筛查出不规则抗体阳性96例,阳性率为0.61%;无妊娠史的2 020例女性患者未检出阳性病例;有输血史与无输血史的患者阳性率比较差异有统计学意义;2.不规则抗体分布中Rh系统的不规则抗体阳性率为93.75%。结论:不规则抗体筛查对输血极其有必要,有过妊娠史和输血史的患者应当特别注意进行筛查,从而成为提高输血安全性的有效措施。
Objective: To investigate the positive rate of irregular antibody in population and its relationship with clinical transfusion. Methods: Totally 15800 patients who applied for clinical transfusion in our hospital from February 2012 to February 2015 were screened for irregular antibody by using microcolumn gel antiglobulin method. Results: 1.15 800 patients were screened out irregular antibody positive in 96 cases, the positive rate was 0.61%; no pregnancy in 2,020 cases of female patients were not detected positive cases; blood transfusion history and no history of blood transfusion in patients with positive rates were significantly different Statistically significant; 2 irregular antibody distribution Rh system irregular antibody positive rate was 93.75%. Conclusion: Irregular antibody screening is extremely necessary for blood transfusion. Patients with history of pregnancy and blood transfusion should pay special attention to screening, which becomes an effective measure to improve blood transfusion safety.