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对36名肿瘤患者(含6名良性肿瘤)手术前后的免疫功能进行了动态观察。检测指标包括 T细胞亚群(T3、T4、T8及 OKT4/OKT8)、单个核细胞细胞毒性因子(MCCF)及血浆淋转抑制因子(PLTIF)。结果表明:手术可明显降低 OKT4亚群,并造成 OKT4/OKT8下降,此种效应维持时间较长;术后 MCCF 活性明显增强,反映了手术的治疗作用;手术后 PLTIF 活性有一过性增加,对其性质需作进一步研究。
Immune function before and after surgery was dynamically observed in 36 cancer patients (including 6 benign tumors). The test parameters included T cell subsets (T3, T4, T8, and OKT4/OKT8), mononuclear cell cytotoxicity factor (MCCF), and plasma leach inhibitory factor (PLTIF). The results showed that: Surgery can significantly reduce OKT4 subgroup, and cause OKT4/OKT8 decline, this effect is maintained for a long time; Postoperative MCCF activity was significantly enhanced, reflecting the surgical treatment; postoperative PLTIF activity has a transient increase, Its nature requires further study.