论文部分内容阅读
目的:探讨妊娠晚期生理性血脂升高的范围和建立妊娠期特异性血脂正常值参考标准的必要性。方法:分析723例正常妊娠晚期孕妇和110例健康非妊娠育龄妇女的血清甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白A1(Apo-A1)和载脂蛋白B(Apo-B)6项指标的水平,比较两组之间的差异,并采用95%参考值范围确定妊娠晚期血脂6项指标生理性升高的参考值范围。结果:①妊娠晚期血脂6项指标均显著高于非妊娠期,差异有统计学意义(P<0.05)。有98.20%的孕妇在孕晚期有不同程度的血脂升高,血脂变化以TG升高为主,升高程度为非妊娠组的4.87倍。②正常妊娠晚期血脂6项指标参考值范围,TG、TC、HDL-C、LDL-C、Apo-A1及Apo-B分别为0.17～6.55 mmol/L、3.67～8.33 mmol/L、1.10～2.62 mmol/L、1.49～4.97 mmol/L、1.39～2.64 g/L及0.61～1.87 g/L。
Objective: To explore the range of physiological blood lipid in the third trimester of pregnancy and the necessity of establishing a reference standard of gestational specific blood lipids. Methods: Serum levels of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL) and serum lipids were measured in 723 pregnant women with normal late pregnancy and 110 healthy women of child- C), apolipoprotein A1 (Apo-A1) and apolipoprotein B (Apo-B) levels were compared between the two groups, and 95% of the reference range was used to identify 6 Physiological indicators of increased reference range. Results: (1) The indexes of serum lipid in the third trimester of pregnancy were significantly higher than those of non-pregnant women (P <0.05). There are 98.20% of pregnant women have different levels of blood lipid in the third trimester of pregnancy, blood lipid changes to TG-based, elevated to non-pregnant group 4.87 times. (2) The reference value of 6 indicators of normal pregnant women’s serum lipids, TG, TC, HDL-C, LDL-C, Apo-A1 and Apo-B were 0.17-6.55 mmol / L, 3.67-8.33 mmol / L, 1.10-2.62 mmol / L, 1.49 ~ 4.97 mmol / L, 1.39 ~ 2.64 g / L and 0.61 ~ 1.87 g / L respectively.