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为了探讨血清免疫球蛋白 (Ig)和载脂蛋白 (Apo)对肾病综合征患者的临床价值 ,利用BECKMAN公司生产的全自动特种蛋白仪和该公司提供的国际标准化试剂盒 ,采取散射浊度速率法检测了 45名健康人和 45名肾病综合征患者。结果 ,肾病综合征组IgG、IgA均显著低于健康对照组 (P <0 0 1) ,IgM变化不大。载脂蛋白B(ApoB)显著开高 (P <0 0 1) ,且载脂蛋白A1(ApoA1)的升高幅度不及B ,A1/B比值显著低于健康对照组 (P <0 0 1)。提示血清免疫球蛋白与载脂蛋白A1、B的检测 ,对肾病综合征的临床诊断、治疗及预后 ,不失为一项较有价值的指标。
In order to investigate the clinical value of serum immunoglobulin (Ig) and apolipoprotein (Apo) in patients with nephrotic syndrome, using the BECKMAN company’s automatic special protein analyzer and the company’s international standardization kit to take the scattering turbidity rate The law tested 45 healthy people and 45 patients with nephrotic syndrome. Results, nephrotic syndrome group IgG, IgA were significantly lower than the healthy control group (P <0 01), IgM little change. Apolipoprotein B (ApoB) was significantly higher (P <0.01), and the increase of ApoA1 was lower than that of B, and the ratio of A1 / B was significantly lower than that of healthy controls (P <0.01) . Prompt serum immunoglobulin and apolipoprotein A1, B detection of nephrotic syndrome, clinical diagnosis, treatment and prognosis, after all, a more valuable indicator.