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目的探讨食物中重金属及氟元素含量与大骨节病的关系,为有效减少大骨节病的发生提供理论依据。方法采集山东省滕州市大骨节病病区与非病区的食物样品,检测其中的重金属及氟元素含量,并对检测结果进行统计学处理。结果病区玉米中Cu、Zn、Pb、As、Cr的含量均显著高于非病区,差异均有统计学意义(P<0.05);病区高粱中Mn、Cu、Cr、Zn、As含量显著高于非病区,差异均有统计学意义(P<0.05);病区玉米及高粱中氟元素含量均显著低于非病区,差异均有统计学意义(P<0.05)。结论病区与非病区食物中多种重金属元素水平有升高表现,氟元素呈较低水平,Cu、Cr、Zn及氟元素与大骨节病发病存在显著关系,对于大骨节病患者可减少Cu、Cr等重金属含量较高的食物的摄入量,并适当补充氟元素,以有效防治大骨节病。
Objective To investigate the relationship between the content of heavy metals and fluoride in food and Kashin-Beck disease, and to provide a theoretical basis for effectively reducing the occurrence of Kashin-Beck disease. Methods Food samples were collected from diseased and non-diseased areas of Kashin-Beck disease in Tengzhou City, Shandong Province. The contents of heavy metals and fluorine in the samples were detected and the results were statistically analyzed. Results The contents of Cu, Zn, Pb, As and Cr in maize were significantly higher than those in non-endemic area (P <0.05). The content of Mn, Cu, Cr, Zn and As in the sorghum (P <0.05). The contents of fluoride in maize and sorghum were significantly lower than those in non-endemic area (P <0.05). Conclusions The contents of trace elements in food in diseased and non-diseased areas are increased. The content of fluoride is low. There is a significant relationship between Cu, Cr, Zn and fluoride and the incidence of Kashin-Beck disease. Cu, Cr and other heavy metal content of food intake, and appropriate fluoride supplement, in order to effectively prevent Kashin-Beck disease.