论文部分内容阅读
目的探讨肾母细胞瘤诊治方法 ,旨在提高患儿存活率。方法回顾性分析本院收治的肾母细胞瘤28例,由小儿外科、肿瘤科、病理科、放射诊断及治疗科联合诊断,28例实施手术、化疗及放疗等方法综合治疗;年龄<1岁,Ⅰ期及Ⅱ期预后良好型不放疗。结果 28例分型:预后良好型21例,预后不良型7例;分期:Ⅰ期2例;Ⅱ期11例;Ⅲ期8例;Ⅳ期7例。随访28例,26例获得有效缓解(92.9%);3年生存率为78.6%(22/28)。6例未获得缓解者均死于疾病进展,无治疗相关性死亡。结论多学科联合诊断、综合治疗肾母细胞瘤可以取得良好疗效。手术是根本的治疗方法 ,术后标准放化疗对于肾母细胞瘤的预后至关重要。
Objective To investigate the diagnosis and treatment of nephroblastoma, aimed at improving the survival rate of children. Methods A retrospective analysis of 28 cases of nephroblastoma treated in our hospital was performed by pediatric surgery, oncology department, pathology department, radiodiagnosis and treatment department, and 28 cases were treated by operation, chemotherapy and radiotherapy. Age <1 year , Ⅰ and Ⅱ prognosis of good type without radiotherapy. Results 28 cases of type: good prognosis in 21 cases, poor prognosis in 7 cases; staging: Ⅰ in 2 cases; Ⅱ in 11 cases; Ⅲ in 8 cases; Ⅳ in 7 cases. Twenty-eight patients were followed up, and 26 patients achieved effective remission (92.9%). The 3-year survival rate was 78.6% (22/28). Six patients who did not receive remission died of disease progression and no treatment-related death. Conclusions Multidisciplinary joint diagnosis and comprehensive treatment of Wilms’ tumor can achieve good curative effect. Surgery is the fundamental treatment, standard radiotherapy and chemotherapy for the prognosis of Wilms tumor is essential.